PCDHB14 antibody (AA 1-374) (Fluoro488)

Catalog No. ABIN8028727

The Fluoro488-conjugated Rabbit Polyclonal anti-PCDHB14 antibody (ABIN8028727) specifically detects PCDHB14 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PCDHB14 antibody (AA 1-374) (Fluoro488) (ABIN8028727)

Target: PCDHB14 (Protocadherin beta 14 (PCDHB14))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHB14 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-PCDHB14 Antibody (Fluoro488)

Binding Specificity: AA 1-374

Purpose: Anti-PCDHB14 Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PCDHB14 recombinant protein (Position: M1-D374).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PCDHB14

Target: PCDHB14 (Protocadherin beta 14 (PCDHB14))

Alternative Name: PCDHB14

Background:

Background: Protocadherin beta-14 is a protein that in humans is encoded by the PCDHB14 gene. This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.

Gene Full Name: protocadherin beta 14

Gene ID: 56122

UniProt: Q9Y5E9