Protocadherin gamma Subfamily C, 3 (PCDHGC3) (AA 498-804) antibody

Catalog No. ABIN8028757

The Rabbit Polyclonal anti-Protocadherin gamma Subfamily C, 3 antibody (ABIN8028757) specifically detects Protocadherin gamma Subfamily C, 3 in WB, ELISA and FACS. The antibody is reactive with Human and Rat samples.

Quick Overview for Protocadherin gamma Subfamily C, 3 (PCDHGC3) (AA 498-804) antibody (ABIN8028757)

Target: Protocadherin gamma Subfamily C, 3 (PCDHGC3)

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Grade: Carrier-free

Product Details

Binding Specificity: AA 498-804

Purpose: Anti-PCDHGC3 Antibody

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Anti-PCDHGC3 Antibody. Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PCDHGC3 recombinant protein (Position: E498-E804).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Rat Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details

Target: Protocadherin gamma Subfamily C, 3 (PCDHGC3)

Alternative Name: PCDHGC3

Background:

Background: Protocadherin gamma-C3 is a protein that in humans is encoded by the PCDHGC3 gene. This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

Gene Full Name: protocadherin gamma subfamily C, 3

Molecular Weight: 118 kDa

Gene ID: 5098

UniProt: Q9UN70