PUM1 antibody (AA 1-361) (Fluoro488)

Catalog No. ABIN8028925

The Fluoro488-conjugated Rabbit Polyclonal anti-PUM1 antibody (ABIN8028925) specifically detects PUM1 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PUM1 antibody (AA 1-361) (Fluoro488) (ABIN8028925)

Target: PUM1 (Pumilio Homolog 1 (PUM1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PUM1 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-PUM1 Antibody (Fluoro488)

Binding Specificity: AA 1-361

Purpose: Anti-PUM1 Antibody Fluoro488 Conjugated

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PUM1 recombinant protein (Position: M1-D361).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PUM1

Target: PUM1 (Pumilio Homolog 1 (PUM1))

Alternative Name: PUM1

Background:

Background: Pumilio homolog 1 is a protein that in humans is encoded by the PUM1 gene. This gene encodes a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. The encoded protein contains a sequence-specific RNA binding domain comprised of eight repeats and N- and C-terminal flanking regions, and serves as a translational regulator of specific mRNAs by binding to their 3' untranslated regions. The evolutionarily conserved function of the encoded protein in invertebrates and lower vertebrates suggests that the human protein may be involved in translational regulation of embryogenesis, and cell development and differentiation. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene Full Name: pumilio RNA binding family member 1

Gene ID: 9698

UniProt: Q14671