P2RY6 antibody (C-Term)

Catalog No. ABIN8029264

The Rabbit Polyclonal anti-P2RY6 antibody (ABIN8029264) specifically detects P2RY6 in WB. The antibody is reactive with Human samples.

Quick Overview for P2RY6 antibody (C-Term) (ABIN8029264)

Target: P2RY6 (Pyrimidinergic Receptor P2Y, G-Protein Coupled, 6 (P2RY6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This P2RY6 antibody is un-conjugated

Application: Western Blotting (WB)

Grade: Carrier-free

Product Details anti-P2RY6 Antibody

Binding Specificity: C-Term

Purpose: Anti-P2Y6/P2RY6 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-P2Y6/P2RY6 Antibody. Tested in WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminusof human P2Y6/P2RY6, which shares 94.4% amino acid (aa) sequence identity with rat P2RY6.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for P2RY6

Target: P2RY6 (Pyrimidinergic Receptor P2Y, G-Protein Coupled, 6 (P2RY6))

Alternative Name: P2RY6

Background:

Background: P2Y purinoceptor 6 is a protein that in humans is encoded by the P2RY6 gene. The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, which is a G-protein coupled receptor, is responsive to UDP, partially responsive to UTP and ADP, and not responsive to ATP. It is proposed that this receptor mediates inflammatory responses. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

Gene Full Name: pyrimidinergic receptor P2Y6

Molecular Weight: 45 kDa

Gene ID: 5031

UniProt: Q15077

Pathways: Smooth Muscle Cell Migration