R-Spondin 4 antibody (AA 60-206) (HRP)

Catalog No. ABIN8029525

The HRP-conjugated Rabbit Polyclonal anti-R-Spondin 4 antibody (ABIN8029525) specifically detects R-Spondin 4 in WB, ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for R-Spondin 4 antibody (AA 60-206) (HRP) (ABIN8029525)

Target: R-Spondin 4 (RSPO4)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This R-Spondin 4 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-R-Spondin 4 Antibody (HRP)

Binding Specificity: AA 60-206

Purpose: Anti-RSPO4 Antibody HRP Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human RSPO4 shares 82.2% amino acid (aa) sequence identity with mouse RSPO4.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human RSPO4 recombinant protein (Position: R60-K206). Human RSPO4 shares 82.2% amino acid (aa) sequence identity with mouse RSPO4.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for R-Spondin 4

Target: R-Spondin 4 (RSPO4)

Alternative Name: RSPO4

Background:

Background: For chromosome 20, R-spondin 4 is a protein in humans that is encoded by the RSPO4 gene. This gene encodes a member of the R-spondin family of proteins that share a common domain organization consisting of a signal peptide, cysteine-rich/furin-like domain, thrombospondin domain and a C-terminal basic region. The encoded protein may be involved in activation of Wnt/beta-catenin signaling pathways. Mutations in this gene are associated with anonychia congenital. Alternate splicing results in multiple transcript variants.

Gene Full Name: R-spondin 4

Gene ID: 343637

UniProt: Q2I0M5