RAB36 antibody (AA 56-323) (APC)

Catalog No. ABIN8029838

This Rabbit Polyclonal antibody specifically detects RAB36 in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for RAB36 antibody (AA 56-323) (APC) (ABIN8029838)

Target: RAB36 (RAB36, Member RAS Oncogene Family (RAB36))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB36 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-RAB36 Antibody (APC)

Binding Specificity: AA 56-323

Purpose: Anti-RAB36 Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human RAB36 recombinant protein (Position: Q56-E323).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for RAB36

Target: RAB36 (RAB36, Member RAS Oncogene Family (RAB36))

Alternative Name: RAB36

Background:

Background: Ras-related protein Rab-36 is a protein that in humans is encoded by the RAB36 gene. The Ras-related superfamily of guanine nucleotide binding proteins includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies. Increasing data suggests an important role for Rab proteins in either endocytosis or in biosynthetic protein transport. The process of transporting newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves the movement of carrier vesicles and requires Rab protein function. Rab proteins are also an integral part of endocytic pathways. Rab 36 is a ubiquitously expressed member of the Rab family of proteins and localizes to the Golgi membrane where it is believed to participate in protein transport. The gene encoding Rab 36 localizes to a critical region of chromosome 22 that is often deleted or involved in translocations in malignant rhabdoid tumors (MRTs). This suggests that Rab 36 may play a role in the development of MRTs.

Gene Full Name: RAB36, member RAS oncogene family

Gene ID: 9609

UniProt: O95755