RAB3IP antibody (AA 25-426) (Biotin)

Catalog No. ABIN8029842

The Rabbit Polyclonal anti-RAB3IP antibody is suitable to detect RAB3IP in samples from Human, Rat and Mouse. It has been validated for ELISA, IHC and WB.

Quick Overview for RAB3IP antibody (AA 25-426) (Biotin) (ABIN8029842)

Target: RAB3IP (RAB3A Interacting Protein (Rabin3) (RAB3IP))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB3IP antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Product Details anti-RAB3IP Antibody (Biotin)

Binding Specificity: AA 25-426

Purpose: Anti-RAB3IP Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human RAB3IP shares 89.6% amino acid (aa) sequence identity with rat RAB3IP.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human RAB3IP recombinant protein (Position: F25-R426). Human RAB3IP shares 89.6% amino acid (aa) sequence identity with rat RAB3IP.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RAB3IP

Target: RAB3IP (RAB3A Interacting Protein (Rabin3) (RAB3IP))

Alternative Name: RAB3IP

Background:

Background: RAB3A-interacting protein is a protein that in humans is encoded by the RAB3IP gene. RAB3IP, also hnown as Rabin8, is a deduced 476-amino acid protein containing a central coiled-coil domain, a bipartite nuclear localization signal, and a C-terminal endoplasmic reticulum retention motif. Rabin8 has several sites for N-glycosylation and phosphorylation. Rabin8 plays important roles in various cellular processes, including ciliogenesis.The GEF activity of Rabin8 towards Rab8 is essential for ciliogenesis and cyst apical membrane transport,but not for exocytosis of discoidal/fusiform-shaped vesicles.

Gene Full Name: RAB3A interacting protein

Gene ID: 117177

UniProt: Q96QF0