RAB6A antibody (C-Term) (Fluoro550)

Catalog No. ABIN8029944

The Rabbit Polyclonal anti-RAB6A antibody is suitable to detect RAB6A in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for RAB6A antibody (C-Term) (Fluoro550) (ABIN8029944)

Target: RAB6A (RAB6A, Member RAS Oncogene Family (RAB6A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB6A antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-RAB6A Antibody (Fluoro550)

Binding Specificity: C-Term

Purpose: Anti-RAB6A Antibody Fluoro550 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human RAB6A, which shares 97.2% amino acid (aa) sequence identity with both mouse and rat RAB6A.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for RAB6A

Target: RAB6A (RAB6A, Member RAS Oncogene Family (RAB6A))

Alternative Name: RAB6A

Background:

Background: Ras-related protein Rab-6A is a protein that in humans is encoded by the RAB6A gene located in the eleventh chromosome. This gene encodes a member of the RAB family, which belongs to the small GTPase superfamily. GTPases of the RAB family bind to various effectors to regulate the targeting and fusion of transport carriers to acceptor compartments. This protein is located at the Golgi apparatus, which regulates trafficking in both a retrograde (from early endosomes and Golgi to the endoplasmic reticulum) and an anterograde (from the Golgi to the plasma membrane) ions. Myosin II is an effector of this protein in these processes. This protein is also involved in assembly of human cytomegalovirus (HCMV) by interacting with the cellular protein Bicaudal D1, which interacts with the HCMV virion tegument protein, pp150. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Gene Full Name: RAB6A, member RAS oncogene family

Gene ID: 5870

UniProt: P20340