RAD21 antibody (AA 292-529) (PE)

Catalog No. ABIN8030070

The Rabbit Polyclonal anti-RAD21 antibody is suitable to detect RAD21 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for RAD21 antibody (AA 292-529) (PE) (ABIN8030070)

Target: RAD21 (RAD21 Homolog (RAD21))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAD21 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-RAD21 Antibody (PE)

Binding Specificity: AA 292-529

Purpose: Anti-RAD21 Antibody PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human RAD21 recombinant protein (Position: D292-K529).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for RAD21

Target: RAD21 (RAD21 Homolog (RAD21))

Alternative Name: RAD21

Background:

Background: Double-strand-break repair protein rad21 homolog is a protein that in humans is encoded by the RAD21 gene. The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells.

Gene Full Name: RAD21 cohesin complex component

Gene ID: 5885

UniProt: O60216

Pathways: Positive Regulation of Endopeptidase Activity