RAD9A antibody (AA 1-389) (Fluoro647)

Catalog No. ABIN8030160

The Rabbit Polyclonal anti-RAD9A antibody is suitable to detect RAD9A in samples from Mouse and Rat. It has been validated for FACS.

Quick Overview for RAD9A antibody (AA 1-389) (Fluoro647) (ABIN8030160)

Target: RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAD9A antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-RAD9A Antibody (Fluoro647)

Binding Specificity: AA 1-389

Purpose: Anti-Rad9/Rad9a Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Rad9/Rad9a recombinant protein (Position: M1-G389).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for RAD9A

Target: RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))

Alternative Name: Rad9a

Background:

Background: This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair. This protein possesses 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: RAD9 checkpoint clamp component A

Gene ID: 19367

UniProt: Q9Z0F6

Pathways: Positive Regulation of Response to DNA Damage Stimulus