RALBP1 antibody (AA 239-506) (HRP)

Catalog No. ABIN8030300

This Mouse Monoclonal antibody specifically detects RALBP1 in WB, IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for RALBP1 antibody (AA 239-506) (HRP) (ABIN8030300)

Target: RALBP1 (RalA Binding Protein 1 (RALBP1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RALBP1 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 2E11

Product Details anti-RALBP1 Antibody (HRP)

Binding Specificity: AA 239-506

Purpose: Anti-RALBP1 Antibody (monoclonal, 2E11) HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human RALBP1 recombinant protein (Position: K239-Q506).

Isotype: IgG2a

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RALBP1

Target: RALBP1 (RalA Binding Protein 1 (RALBP1))

Alternative Name: RALBP1

Background:

Background: RalA-binding protein 1 is a protein that in humans is encoded by the RALBP1 gene. Small G proteins, such as RAL, have GDP-bound inactive and GTP-bound active forms, which shift from the inactive to the active state through the action of RALGDS, which in turn is activated by RAS. RALBP1 plays a role in receptor-mediated endocytosis and is a downstream effector of the small GTP-binding protein RAL. RALBP1 is also the dominant transporter of lipid peroxidation-derived glutathione conjugates and participates in several mitotic events, including inactivation of endocytosis and separation and polar movement of centrioles and appropriate distribution of mitochondria to daughter cells following mitosis.

Gene Full Name: ralA binding protein 1

Gene ID: 10928

UniProt: Q15311