RALBP1 antibody (AA 239-506) (APC)

Catalog No. ABIN8030301

The Mouse Monoclonal anti-RALBP1 antibody is suitable to detect RALBP1 in samples from Human. It has been validated for FACS.

Quick Overview for RALBP1 antibody (AA 239-506) (APC) (ABIN8030301)

Target: RALBP1 (RalA Binding Protein 1 (RALBP1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RALBP1 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Clone: 2E11

Product Details anti-RALBP1 Antibody (APC)

Binding Specificity: AA 239-506

Purpose: Anti-RALBP1 Antibody (monoclonal, 2E11) APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human RALBP1 recombinant protein (Position: K239-Q506).

Isotype: IgG2a

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for RALBP1

Target: RALBP1 (RalA Binding Protein 1 (RALBP1))

Alternative Name: RALBP1

Background:

Background: RalA-binding protein 1 is a protein that in humans is encoded by the RALBP1 gene. Small G proteins, such as RAL, have GDP-bound inactive and GTP-bound active forms, which shift from the inactive to the active state through the action of RALGDS, which in turn is activated by RAS. RALBP1 plays a role in receptor-mediated endocytosis and is a downstream effector of the small GTP-binding protein RAL. RALBP1 is also the dominant transporter of lipid peroxidation-derived glutathione conjugates and participates in several mitotic events, including inactivation of endocytosis and separation and polar movement of centrioles and appropriate distribution of mitochondria to daughter cells following mitosis.

Gene Full Name: ralA binding protein 1

Gene ID: 10928

UniProt: Q15311