RORB antibody (AA 236-470) (FITC)

Catalog No. ABIN8030532

The Rabbit Polyclonal anti-RORB antibody is suitable to detect RORB in samples from Human. It has been validated for FACS.

Quick Overview for RORB antibody (AA 236-470) (FITC) (ABIN8030532)

Target: RORB (RAR-Related Orphan Receptor B (RORB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RORB antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Product Details anti-RORB Antibody (FITC)

Binding Specificity: AA 236-470

Purpose: Anti-ROR beta/RORB Antibody FITC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human ROR beta/RORB recombinant protein (Position: E236-K470).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for RORB

Target: RORB (RAR-Related Orphan Receptor B (RORB))

Alternative Name: RORB

Background:

Background: RAR-related orphan receptor beta (ROR-beta), also known as NR1F2 (nuclear receptor subfamily 1, group F, member 2) is a nuclear receptor that in humans is encoded by the RORB gene. The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, and to help regulate the expression of some genes involved in circadian rhythm.

Gene Full Name: RAR related orphan receptor B

Gene ID: 6096

UniProt: Q92753

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway