RASD1 antibody (AA 1-281) (Fluoro647)

Catalog No. ABIN8030813

This Rabbit Polyclonal antibody specifically detects RASD1 in FACS. It exhibits reactivity toward Mouse, Human and Rat.

Quick Overview for RASD1 antibody (AA 1-281) (Fluoro647) (ABIN8030813)

Target: RASD1 (RAS, Dexamethasone-Induced 1 (RASD1))

Reactivity: Mouse, Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RASD1 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-RASD1 Antibody (Fluoro647)

Binding Specificity: AA 1-281

Purpose: Anti-Dexras1/RASD1 Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Dexras1/RASD1 recombinant protein (Position: M1-S281).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for RASD1

Target: RASD1 (RAS, Dexamethasone-Induced 1 (RASD1))

Alternative Name: RASD1

Background:

Background: Dexamethasone-induced Ras-related protein 1 (RASD1) is a protein that in humans is encoded by the RASD1 gene on chromosome 17. This gene encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone. The encoded protein is an activator of G-protein signaling and acts as a nucleotide exchange factor for Gi-Go proteins. This protein interacts with the neuronal nitric oxide adaptor protein CAPON, and a nuclear adaptor protein FE65, which interacts with the Alzheimer's disease amyloid precursor protein. This gene may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. Epigenetic inactivation of this gene is closely correlated with resistance to dexamethasone in multiple myeloma cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: ras related dexamethasone induced 1

Gene ID: 51655

UniProt: Q9Y272