RCC1 antibody (AA 14-421) (Fluoro488)

Catalog No. ABIN8031103

The Fluoro488-conjugated Mouse Monoclonal anti-RCC1 antibody (Clone 7B5D2) (ABIN8031103) specifically detects RCC1 in FACS. The antibody is reactive with Human samples.

Quick Overview for RCC1 antibody (AA 14-421) (Fluoro488) (ABIN8031103)

Target: RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RCC1 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Clone: 7B5D2

Product Details anti-RCC1 Antibody (Fluoro488)

Binding Specificity: AA 14-421

Purpose: Anti-RCC1 Antibody (monoclonal, 7B5D2) Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human RCC1 recombinant protein (Position: A14-S421).

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for RCC1

Target: RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

Alternative Name: RCC1

Background:

Background: CHC1, also named as RCC1, SNHG3-RCC1, promotes the exchange of ran-bound gdp by gtp. It is involved in the regulation of onset of chromosome condensation in the S-phase. Phosphorylation of RCC1 on serines located in or near its nuclear localization signal activates RCC1 to generate RanGTP on mitotic chromosomes, which is required for spindle assembly and chromosome segregation. This antibody is a rabbit polyclonal antibody raised against residues near the C terminus of human RCC1. The geneID has updated as 1104 recently.

Gene Full Name: regulator of chromosome condensation 1

Gene ID: 1104

UniProt: P18754

Pathways: Chromatin Binding, Protein targeting to Nucleus