RTEL1 antibody (AA 651-756)

Catalog No. ABIN8031232

The Rabbit Polyclonal anti-RTEL1 antibody (ABIN8031232) specifically detects RTEL1 in ELISA and WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for RTEL1 antibody (AA 651-756) (ABIN8031232)

Target: RTEL1 (Regulator of Telomere Elongation Helicase 1 (RTEL1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RTEL1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Grade: Carrier-free

Product Details anti-RTEL1 Antibody

Binding Specificity: AA 651-756

Purpose: Anti-RTEL1 Antibody

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-RTEL1 Antibody. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human RTEL1 recombinant protein (Position: R651-M756).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for RTEL1

Target: RTEL1 (Regulator of Telomere Elongation Helicase 1 (RTEL1))

Alternative Name: RTEL1

Background:

Background: The RTEL1 gene encodes a DNA helicase which functions in the stability, protection and elongation of telomeres and interacts with proteins in the shelterin complex known to protect telomeres during DNA replication. Mutations in this gene have been associated with dyskeratosis congenita and Hoyerall-Hreidarsson syndrome. Read-through transcription of this gene into the neighboring downstream gene, which encodes tumor necrosis factor receptor superfamily, member 6b, generates a non-coding transcript. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Full Name: regulator of telomere elongation helicase 1

Molecular Weight: 134 kDa

Gene ID: 51750

UniProt: Q9NZ71