c-Rel antibody (AA 116-610) (PE)

Catalog No. ABIN8031318

The Rabbit Polyclonal anti-c-Rel antibody is suitable to detect c-Rel in samples from Human. It has been validated for FACS.

Quick Overview for c-Rel antibody (AA 116-610) (PE) (ABIN8031318)

Target: c-Rel (REL proto-oncogene (c-Rel))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This c-Rel antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-c-Rel Antibody (PE)

Binding Specificity: AA 116-610

Purpose: Anti-c-Rel/REL Antibody PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human c-Rel/REL recombinant protein (Position: K116-D610).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for c-Rel

Target: c-Rel (REL proto-oncogene (c-Rel))

Alternative Name: REL

Background:

Background: The proto-oncogene c-Rel is a protein that in humans is encoded by the REL gene This gene encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold, plexin, transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of this gene is associated with B-cell lymphomas, including Hodgkin's lymphoma. Single nucleotide polymorphisms in this gene are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Full Name: REL proto-oncogene, NF-kB subunit

Gene ID: 5966

UniProt: Q04864