RTN4R antibody (AA 56-416) (Fluoro488)

Catalog No. ABIN8031676

The Fluoro488-conjugated Rabbit Polyclonal anti-RTN4R antibody (ABIN8031676) specifically detects RTN4R in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for RTN4R antibody (AA 56-416) (Fluoro488) (ABIN8031676)

Target: RTN4R (Reticulon 4 Receptor (RTN4R))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RTN4R antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-RTN4R Antibody (Fluoro488)

Binding Specificity: AA 56-416

Purpose: Anti-Nogo receptor/NgR1/RTN4R Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Nogo receptor/NgR1/RTN4R recombinant protein (Position: P56-R416).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for RTN4R

Target: RTN4R (Reticulon 4 Receptor (RTN4R))

Alternative Name: RTN4R

Background:

Background: Reticulon 4 receptor (RTN4R) also known as Nogo-66 Receptor (NgR) or Nogo receptor 1 is a protein which in humans is encoded by the RTN4R gene. This gene encodes the receptor for reticulon 4, oligodendrocyte myelin glycoprotein and myelin-associated glycoprotein. This receptor mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system.

Gene Full Name: reticulon 4 receptor

Gene ID: 65078

UniProt: Q9BZR6

Pathways: Neurotrophin Signaling Pathway