RPGR antibody (AA 13-338) (FITC)

Catalog No. ABIN8031757

The FITC-conjugated Rabbit Polyclonal anti-RPGR antibody (ABIN8031757) specifically detects RPGR in FACS. The antibody is reactive with Rat samples.

Quick Overview for RPGR antibody (AA 13-338) (FITC) (ABIN8031757)

Target: RPGR (Retinitis Pigmentosa GTPase Regulator (RPGR))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPGR antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Product Details anti-RPGR Antibody (FITC)

Binding Specificity: AA 13-338

Purpose: Anti-RPGR Antibody FITC Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human RPGR recombinant protein (Position: A13-F338).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for RPGR

Target: RPGR (Retinitis Pigmentosa GTPase Regulator (RPGR))

Alternative Name: RPGR

Background:

Background: X-linked retinitis pigmentosa GTPase regulator is a GTPase-binding protein that in humans is encoded by the RPGR gene. This gene encodes a protein with a series of six RCC1-like domains (RLDs), characteristic of the highly conserved guanine nucleotide exchange factors. The encoded protein is found in the Golgi body and interacts with RPGRIP1. This protein localizes to the outer segment of rod photoreceptors and is essential for their viability. Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP). Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length natures of only some have been determined.

Gene Full Name: retinitis pigmentosa GTPase regulator

Gene ID: 6103

UniProt: Q92834