RPGR antibody (AA 13-338)

Catalog No. ABIN8031762

The Rabbit Polyclonal anti-RPGR antibody is suitable to detect RPGR in samples from Rat. It has been validated for WB and ELISA.

Quick Overview for RPGR antibody (AA 13-338) (ABIN8031762)

Target: RPGR (Retinitis Pigmentosa GTPase Regulator (RPGR))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPGR antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Carrier-free

Product Details anti-RPGR Antibody

Binding Specificity: AA 13-338

Purpose: Anti-RPGR Antibody

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-RPGR Antibody. Tested in ELISA, WB applications. This antibody reacts with Rat.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human RPGR recombinant protein (Position: A13-F338).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for RPGR

Target: RPGR (Retinitis Pigmentosa GTPase Regulator (RPGR))

Alternative Name: RPGR

Background:

Background: X-linked retinitis pigmentosa GTPase regulator is a GTPase-binding protein that in humans is encoded by the RPGR gene. This gene encodes a protein with a series of six RCC1-like domains (RLDs), characteristic of the highly conserved guanine nucleotide exchange factors. The encoded protein is found in the Golgi body and interacts with RPGRIP1. This protein localizes to the outer segment of rod photoreceptors and is essential for their viability. Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP). Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length natures of only some have been determined.

Gene Full Name: retinitis pigmentosa GTPase regulator

Molecular Weight: 113 kDa

Gene ID: 6103

UniProt: Q92834