RS1 antibody (AA 34-224) (Fluoro647)

Catalog No. ABIN8031994

The Fluoro647-conjugated Rabbit Polyclonal anti-RS1 antibody (ABIN8031994) specifically detects RS1 in FACS. The antibody is reactive with Human and Mouse samples.

Quick Overview for RS1 antibody (AA 34-224) (Fluoro647) (ABIN8031994)

Target: RS1 (Retinoschisin 1 (RS1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RS1 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-RS1 Antibody (Fluoro647)

Binding Specificity: AA 34-224

Purpose: Anti-RS1 Antibody Fluoro647 Conjugated

Predicted Reactivity: Human RS1 shares 96.9% amino acid (aa) sequence identity with mouse RS1.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human RS1 recombinant protein (Position: Y34-A224). Human RS1 shares 96.9% amino acid (aa) sequence identity with mouse RS1.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for RS1

Target: RS1 (Retinoschisin 1 (RS1))

Alternative Name: RS1

Background:

Background: Retinoschisin also known as X-linked juvenile retinoschisis protein is a lectin that in humans is encoded by the RS1 gene. This gene encodes an extracellular protein that plays a crucial role in the cellular organization of the retina. The encoded protein is assembled and secreted from photoreceptors and bipolar cells as a homo-oligomeric protein complex. Mutations in this gene are responsible for X-linked retinoschisis, a common, early-onset macular degeneration in males that results in a splitting of the inner layers of the retina and severe loss in vision.

Gene Full Name: retinoschisin 1

Gene ID: 6247

UniProt: O15537