RhoF antibody (AA 39-204) (PE)

Catalog No. ABIN8032257

The Rabbit Polyclonal anti-RhoF antibody is suitable to detect RhoF in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for RhoF antibody (AA 39-204) (PE) (ABIN8032257)

Target: RhoF (RHOF) (Rho-related GTP-binding protein RhoF (RHOF))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RhoF antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-RhoF Antibody (PE)

Binding Specificity: AA 39-204

Purpose: Anti-RHOF Antibody PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human RHOF recombinant protein (Position: Y39-K204).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for RhoF

Target: RhoF (RHOF) (Rho-related GTP-binding protein RhoF (RHOF))

Alternative Name: RHOF

Background:

Background: Rho, the Ras-related small GTPase, is responsible for the regulation of actin-based cytoskeletal structures including stress fibers, focal adhesions and the contractile ring apparatus. Rho proteins function as molecular switches that are able to turn cytokinesis on and off. Although little is known about signaling downstream of Rho, a host of putative Rho effector proteins have been described. Rho F (ras homolog gene family, member F), also known as RIF or ARHF, is a 211 amino acid membrane protein that localizes to the cytoplasmic side of the plasma membrane. Belonging to the small GTPase superfamily and the Rho family, Rho F functions cooperatively with Cdc42 and Rac to generate additional cytoskeletal structures, such as increasing variation of actin-based morphology. Rho F exists as two alternatively spliced isoforms and is encoded by a gene located on human chromosome 12q24.31.

Gene Full Name: ras homolog family member F, filopodia associated

Gene ID: 54509

UniProt: Q9HBH0