RNASEH2B antibody (AA 39-260) (Fluoro488)

Catalog No. ABIN8032328

This Rabbit Polyclonal antibody specifically detects RNASEH2B in FACS. It exhibits reactivity toward Human.

Quick Overview for RNASEH2B antibody (AA 39-260) (Fluoro488) (ABIN8032328)

Target: RNASEH2B (Ribonuclease H2, Subunit B (RNASEH2B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNASEH2B antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-RNASEH2B Antibody (Fluoro488)

Binding Specificity: AA 39-260

Purpose: Anti-RNASEH2B Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human RNASEH2B recombinant protein (Position: K39-E260).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for RNASEH2B

Target: RNASEH2B (Ribonuclease H2, Subunit B (RNASEH2B))

Alternative Name: RNASEH2B

Background:

Background: Ribonuclease H2, subunit B is a protein that in humans is encoded by the RNASEH2B gene. RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. The protein encoded by this gene is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Aicardi-Goutieres syndrome type 2 (AGS2).

Gene Full Name: ribonuclease H2 subunit B

Gene ID: 79621

UniProt: Q5TBB1