RNASEH2B antibody (AA 39-260)

Catalog No. ABIN8032336

The Rabbit Polyclonal anti-RNASEH2B antibody (ABIN8032336) specifically detects RNASEH2B in WB, ELISA, IF, ICC and FACS. The antibody is reactive with Human samples.

Quick Overview for RNASEH2B antibody (AA 39-260) (ABIN8032336)

Target: RNASEH2B (Ribonuclease H2, Subunit B (RNASEH2B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNASEH2B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Grade: Carrier-free

Product Details anti-RNASEH2B Antibody

Binding Specificity: AA 39-260

Purpose: Anti-RNASEH2B Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-RNASEH2B Antibody. Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human RNASEH2B recombinant protein (Position: K39-E260).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RNASEH2B

Target: RNASEH2B (Ribonuclease H2, Subunit B (RNASEH2B))

Alternative Name: RNASEH2B

Background:

Background: Ribonuclease H2, subunit B is a protein that in humans is encoded by the RNASEH2B gene. RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. The protein encoded by this gene is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Aicardi-Goutieres syndrome type 2 (AGS2).

Gene Full Name: ribonuclease H2 subunit B

Molecular Weight: 35 kDa

Gene ID: 79621

UniProt: Q5TBB1