RNASEL antibody (AA 24-735)

Catalog No. ABIN8032347

The Rabbit Polyclonal anti-RNASEL antibody is suitable to detect RNASEL in samples from Mouse and Rat. It has been validated for WB, ELISA and FACS.

Quick Overview for RNASEL antibody (AA 24-735) (ABIN8032347)

Target: RNASEL (Ribonuclease L (2',5'-Oligoisoadenylate Synthetase-Dependent) (RNASEL))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNASEL antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Grade: Carrier-free

Product Details anti-RNASEL Antibody

Binding Specificity: AA 24-735

Purpose: Anti-RNase L/Rnasel Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-RNase L/Rnasel Antibody. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse RNase L/Rnasel recombinant protein (Position: E24-S735).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Mouse Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Mouse, Rat ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for RNASEL

Target: RNASEL (Ribonuclease L (2',5'-Oligoisoadenylate Synthetase-Dependent) (RNASEL))

Alternative Name: Rnasel

Background:

Background: RNase L is an enzyme that in humans is encoded by the RNASEL gene. This gene encodes a component of the interferon-regulated 2-5A system that functions in the antiviral and antiproliferative roles of interferons. Mutations in this gene have been associated with predisposition to prostate cancer and this gene is a candidate for the hereditary prostate cancer 1 (HPC1) allele.

Gene Full Name: ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)

Molecular Weight: 83 kDa

Gene ID: 24014

UniProt: Q05921

Pathways: Hepatitis C