RRM1 antibody (AA 129-730) (PE)

Catalog No. ABIN8032434

The Rabbit Polyclonal anti-RRM1 antibody is suitable to detect RRM1 in samples from Human. It has been validated for FACS.

Quick Overview for RRM1 antibody (AA 129-730) (PE) (ABIN8032434)

Target: RRM1 (Ribonucleotide Reductase M1 (RRM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RRM1 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-RRM1 Antibody (PE)

Binding Specificity: AA 129-730

Purpose: Anti-RRM1 Antibody PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human RRM1 recombinant protein (Position: D129-Q730).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for RRM1

Target: RRM1 (Ribonucleotide Reductase M1 (RRM1))

Alternative Name: RRM1

Background:

Background: Ribonucleoside-diphosphate reductase large subunit is an enzyme that in humans is encoded by the RRM1 gene. This gene encodes the large and catalytic subunit of ribonucleotide reductase, an enzyme essential for the conversion of ribonucleotides into deoxyribonucleotides. A pool of available deoxyribonucleotides is important for DNA replication during S phase of the cell cycle as well as multiple DNA repair processes. Alternative splicing results in multiple transcript variants.

Gene Full Name: ribonucleotide reductase catalytic subunit M1

Gene ID: 6240

UniProt: P23921

Pathways: Positive Regulation of Endopeptidase Activity