RPS19 antibody (AA 1-145) (Cy3)

Catalog No. ABIN8032801

The Cy3-conjugated Rabbit Polyclonal anti-RPS19 antibody (ABIN8032801) specifically detects RPS19 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for RPS19 antibody (AA 1-145) (Cy3) (ABIN8032801)

Target: RPS19 (Ribosomal Protein S19 (RPS19))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPS19 antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-RPS19 Antibody (Cy3)

Binding Specificity: AA 1-145

Purpose: Anti-RPS19 Antibody Cy3 Conjugated

Predicted Reactivity: Human RPS19 shares 99.3% amino acid (aa) sequence identity with both mouse,rat RPS19.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human RPS19 recombinant protein (Position: M1-H145). Human RPS19 shares 99.3% amino acid (aa) sequence identity with both mouse and rat RPS19.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for RPS19

Target: RPS19 (Ribosomal Protein S19 (RPS19))

Alternative Name: RPS19

Background:

Background: 40S ribosomal protein S19 is a protein that in humans is encoded by the RPS19 gene. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia (DBA), a constitutional erythroblastopenia characterized by absent or decreased erythroid precursors, in a subset of patients. This suggests a possible extra-ribosomal function for this gene in erythropoietic differentiation and proliferation, in addition to its ribosomal function. Higher expression levels of this gene in some primary colon carcinomas compared to matched normal colon tissues has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Gene Full Name: ribosomal protein S19

Gene ID: 6223

UniProt: P39019

Pathways: Positive Regulation of Immune Effector Process, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly