RBM8A antibody (Middle Region)

Catalog No. ABIN8033686

The Rabbit Polyclonal anti-RBM8A antibody (ABIN8033686) specifically detects RBM8A in WB. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for RBM8A antibody (Middle Region) (ABIN8033686)

Target: RBM8A (RNA Binding Motif Protein 8A (RBM8A))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RBM8A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RBM8A Antibody

Binding Specificity: Middle Region

Purpose: Anti-Y14/RBM8A Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-Y14/RBM8A Antibody. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human Y14/RBM8A.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RBM8A

Target: RBM8A (RNA Binding Motif Protein 8A (RBM8A))

Alternative Name: RBM8A

Background:

Background: This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B, it is now thought that the RBM8B locus is a pseudogene. There are two alternate translation start codons with this gene, which result in two forms of the protein. An allele mutation and a low-frequency noncoding single-nucleotide polymorphism (SNP) in this gene cause thrombocytopenia-absent radius (TAR) syndrome.

Gene Full Name: RNA binding motif protein 8A

Molecular Weight: 21 kDa

Gene ID: 9939

UniProt: Q9Y5S9