RBM9 antibody (AA 1-256) (Fluoro647)

Catalog No. ABIN8033718

The Rabbit Polyclonal anti-RBM9 antibody is suitable to detect RBM9 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for RBM9 antibody (AA 1-256) (Fluoro647) (ABIN8033718)

Target: RBM9 (RNA Binding Motif Protein 9 (RBM9))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RBM9 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-RBM9 Antibody (Fluoro647)

Binding Specificity: AA 1-256

Purpose: Anti-FOX2/RBM9/RBFOX2 Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human FOX2/RBM9/RBFOX2 recombinant protein (Position: M1-Y256).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for RBM9

Target: RBM9 (RNA Binding Motif Protein 9 (RBM9))

Alternative Name: RBFOX2

Background:

Background: RNA binding motif protein 9 (RBM9), also known as Rbfox2, is a protein which in humans is encoded by the RBM9 gene. It is mapped to 22q12.3. This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: RNA binding fox-1 homolog 2

Gene ID: 23543

UniProt: O43251

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Skeletal Muscle Fiber Development