NOB1 antibody (AA 1-389) (HRP)

Catalog No. ABIN8033880

The Rabbit Polyclonal anti-NOB1 antibody is suitable to detect NOB1 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IHC.

Quick Overview for NOB1 antibody (AA 1-389) (HRP) (ABIN8033880)

Target: NOB1 (RNA-Binding Protein NOB1 (NOB1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NOB1 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-NOB1 Antibody (HRP)

Binding Specificity: AA 1-389

Purpose: Anti-NOB1 Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NOB1 recombinant protein (Position: M1-D389).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for NOB1

Target: NOB1 (RNA-Binding Protein NOB1 (NOB1))

Alternative Name: NOB1

Background:

Background: RNA-binding protein NOB1 is a protein that in humans is encoded by the NOB1 gene. In yeast, over 200 protein and RNA cofactors are required for ribosome assembly, and these are generally conserved in eukaryotes. These factors orchestrate modification and cleavage of the initial 35S precursor rRNA transcript into the mature 18S, 5.8S, and 25S rRNAs, folding of the rRNA, and binding of ribosomal proteins and 5S RNA. Nob1 is involved in pre-rRNA processing. In a late cytoplasmic processing step, Nob1 cleaves a 20S rRNA intermediate at cleavage site D to produce the mature 18S rRNA.

Gene Full Name: NIN1 (RPN12) binding protein 1 homolog

Gene ID: 28987

UniProt: Q9ULX3

Pathways: Protein targeting to Nucleus