RUFY3 antibody (AA 1-469) (APC)

Catalog No. ABIN8034059

This Rabbit Polyclonal antibody specifically detects RUFY3 in FACS. It exhibits reactivity toward Mouse, Human and Rat.

Quick Overview for RUFY3 antibody (AA 1-469) (APC) (ABIN8034059)

Target: RUFY3 (RUN and FYVE Domain Containing 3 (RUFY3))

Reactivity: Mouse, Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RUFY3 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-RUFY3 Antibody (APC)

Binding Specificity: AA 1-469

Purpose: Anti-RUFY3 Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human RUFY3 recombinant protein (Position: M1-H469).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for RUFY3

Target: RUFY3 (RUN and FYVE Domain Containing 3 (RUFY3))

Alternative Name: RUFY3

Background:

Background: This gene encodes a RPIP8, UNC-14, and NESCA domain-containing protein that is required for maintenance of neuronal polarity. In addition, it has been implicated in mediation of gastric cancer cell migration and invasion via interaction with P21-activated kinase-1, which promotes its expression. The encoded protein localizes to F-actin-enriched invadopodia to induce formation of protrusions, thereby facilitating cell migration. Alternative splicing results in multiple transcript variants.

Gene Full Name: RUN and FYVE domain containing 3

Gene ID: 22902

UniProt: Q7L099