RUFY3 antibody (AA 1-469)

Catalog No. ABIN8034062

This Rabbit Polyclonal antibody specifically detects RUFY3 in WB, ELISA and FACS. It exhibits reactivity toward Mouse, Human and Rat.

Quick Overview for RUFY3 antibody (AA 1-469) (ABIN8034062)

Target: RUFY3 (RUN and FYVE Domain Containing 3 (RUFY3))

Reactivity: Mouse, Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RUFY3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Grade: Carrier-free

Product Details anti-RUFY3 Antibody

Binding Specificity: AA 1-469

Purpose: Anti-RUFY3 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-RUFY3 Antibody. Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human RUFY3 recombinant protein (Position: M1-H469).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg /1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RUFY3

Target: RUFY3 (RUN and FYVE Domain Containing 3 (RUFY3))

Alternative Name: RUFY3

Background:

Background: This gene encodes a RPIP8, UNC-14, and NESCA domain-containing protein that is required for maintenance of neuronal polarity. In addition, it has been implicated in mediation of gastric cancer cell migration and invasion via interaction with P21-activated kinase-1, which promotes its expression. The encoded protein localizes to F-actin-enriched invadopodia to induce formation of protrusions, thereby facilitating cell migration. Alternative splicing results in multiple transcript variants.

Gene Full Name: RUN and FYVE domain containing 3

Molecular Weight: 53-65 kDa

Gene ID: 22902

UniProt: Q7L099