S100A12 antibody (C-Term)

Catalog No. ABIN8034293

This Rabbit Polyclonal antibody specifically detects S100A12 in IHC. It exhibits reactivity toward Human.

Quick Overview for S100A12 antibody (C-Term) (ABIN8034293)

Target: S100A12 (S100 Calcium Binding Protein A12 (S100A12))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This S100A12 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Grade: Carrier-free

Product Details anti-S100A12 Antibody

Binding Specificity: C-Term

Purpose: Anti-S100A12 Antibody

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Anti-S100A12 Antibody. Tested in IHC application. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human S100A12.

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry (Paraffin-embedded Section), 1-2 μg/mL, Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for S100A12

Target: S100A12 (S100 Calcium Binding Protein A12 (S100A12))

Alternative Name: S100A12

Background:

Background: S100 calcium-binding protein A12 (S100A12) is a protein that in humans is encoded by the S100A12 gene. The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. The protein includes an antimicrobial peptide which has antibacterial activity.

Gene Full Name: S100 calcium binding protein A12

Molecular Weight: 56,60 kDa

Gene ID: 6283

UniProt: P80511

Pathways: Toll-Like Receptors Cascades, S100 Proteins