SIK1 antibody (AA 1-783) (APC)

Catalog No. ABIN8034455

This Rabbit Polyclonal antibody specifically detects SIK1 in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for SIK1 antibody (AA 1-783) (APC) (ABIN8034455)

Target: SIK1 (Salt-Inducible Kinase 1 (SIK1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIK1 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-SIK1 Antibody (APC)

Binding Specificity: AA 1-783

Purpose: Anti-Snf1lk/SIK1 Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human Snf1lk,SIK1 shares 80.5%,81.2% amino acid (aa) sequence identity with mouse,rat Snf1lk,SIK1,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Snf1lk/SIK1 recombinant protein (Position: M1-Q783). Human Snf1lk/SIK1 shares 80.5% and 81.2% amino acid (aa) sequence identity with mouse and rat Snf1lk/SIK1, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SIK1

Target: SIK1 (Salt-Inducible Kinase 1 (SIK1))

Alternative Name: SIK1

Background:

Background: This gene encodes a serine/threonine protein kinase that contains a ubiquitin-associated (UBA) domain. The encoded protein is a member of the adenosine monophosphate-activated kinase (AMPK) subfamily of kinases that play a role in conserved signal transduction pathways. A mutation in this gene is associated with early infantile epileptic encephalopathy 30.

Gene Full Name: salt inducible kinase 1B (putative)

Gene ID: 150094

UniProt: P57059

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process