SGCB antibody (AA 101-318) (Cy3)

Catalog No. ABIN8034548

This Rabbit Polyclonal antibody specifically detects SGCB in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for SGCB antibody (AA 101-318) (Cy3) (ABIN8034548)

Target: SGCB (Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGCB antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-SGCB Antibody (Cy3)

Binding Specificity: AA 101-318

Purpose: Anti-Beta Sarcoglycan/SGCB Antibody Cy3 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human Beta Sarcoglycan,SGCB shares 95.4% amino acid (aa) sequence identity with mouse Beta Sarcoglycan,SGCB.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Beta Sarcoglycan/SGCB recombinant protein (Position: E101-H318). Human Beta Sarcoglycan/SGCB shares 95.4% amino acid (aa) sequence identity with mouse Beta Sarcoglycan/SGCB.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SGCB

Target: SGCB (Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB))

Alternative Name: SGCB

Background:

Background: This gene encodes a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix. Mutations in this gene have been associated with limb-girdle muscular dystrophy.

Gene Full Name: sarcoglycan beta

Gene ID: 6443

UniProt: Q16585

Pathways: Myometrial Relaxation and Contraction, Maintenance of Protein Location