Scinderin antibody (AA 35-617)

Catalog No. ABIN8034789

The Rabbit Polyclonal anti-Scinderin antibody is suitable to detect Scinderin in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for Scinderin antibody (AA 35-617) (ABIN8034789)

Target: Scinderin (SCIN)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Scinderin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Carrier-free

Product Details anti-Scinderin Antibody

Binding Specificity: AA 35-617

Purpose: Anti-SCIN Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-SCIN Antibody. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SCIN recombinant protein (Position: S35-Y617).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Scinderin

Target: Scinderin (SCIN)

Alternative Name: SCIN

Background:

Background: Scinderin (also known as adseverin) is a protein that in humans is encoded by the SCIN gene. Ca(2+)-dependent actin filament-severing protein that is presumed to have a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane. In vitro, also has barbed end capping and nucleating activities in the presence of Ca(2+). Regulates chondrocyte proliferation and differentiation. MAP kinases p38 and ERK1/2 mediate the adseverin-induced accelerated differentiation of non-hypertrophic chondrocytes (By similarity).

Gene Full Name: scinderin

Molecular Weight: 80 kDa

Gene ID: 85477

UniProt: Q9Y6U3

Pathways: Regulation of Actin Filament Polymerization