SFRP4 antibody (AA 140-346) (Cy3)

Catalog No. ABIN8035110

The Rabbit Polyclonal anti-SFRP4 antibody is suitable to detect SFRP4 in samples from Human and Rat. It has been validated for FACS.

Quick Overview for SFRP4 antibody (AA 140-346) (Cy3) (ABIN8035110)

Target: SFRP4 (Secreted Frizzled-Related Protein 4 (SFRP4))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SFRP4 antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-SFRP4 Antibody (Cy3)

Binding Specificity: AA 140-346

Purpose: Anti-SFRP4 Antibody Cy3 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human SFRP4 shares 90%,90.3% amino acid (aa) sequence identity with mouse,rat SFRP4,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SFRP4 recombinant protein (Position: E140-V346). Human SFRP4 shares 90% and 90.3% amino acid (aa) sequence identity with mouse and rat SFRP4, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SFRP4

Target: SFRP4 (Secreted Frizzled-Related Protein 4 (SFRP4))

Alternative Name: SFRP4

Background:

Background: Secreted frizzled-related protein 4 (SFRP4) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. It is mappaead to 7p14.1. The expression of SFRP4 in ventricular myocardium correlates with apoptosis related gene expression. And SFRP4 is a hub gene in a Type 2 Diabetes-associated gene coexpression module in human islets, and reduces glucose-induced insulin secretion through decreased β-cell exocytosis.

Gene Full Name: secreted frizzled related protein 4

Sequence Similarities: Belongs to the secreted frizzled-related protein (sFRP) family.

Gene ID: 6424

UniProt: Q6FHJ7

Pathways: WNT Signaling