SCG3 antibody (C-Term) (Fluoro647)

Catalog No. ABIN8035250

This Rabbit Polyclonal antibody specifically detects SCG3 in FACS. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for SCG3 antibody (C-Term) (Fluoro647) (ABIN8035250)

Target: SCG3 (Secretogranin III (SCG3))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCG3 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-SCG3 Antibody (Fluoro647)

Binding Specificity: C-Term

Purpose: Anti-Secretogranin 3/SCG3 Antibody Fluoro647 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: different from the related mouse,rat sequences by one amino acid.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Secretogranin 3, different from the related mouse and rat sequences by one amino acid.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SCG3

Target: SCG3 (Secretogranin III (SCG3))

Alternative Name: SCG3

Background:

Background: SCG3 (secretogranin III) is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Genetic variations in the SCG3 gene may influence the risk of obesity through possible regulation of hypothalamic neuropeptide secretion. SCG3 was the only gene within a haplotype block that contained rs3764220. SCG3 mRNA and immunoreactivity were detected in the paraventricular nucleus, lateral hypothalamic area, and arcuate nucleus, and the protein coexisted with orexin, melanin-concentrating hormone, neuropeptide Y, and proopiomelanocortin. SCG3 formed a granule-like structure together with these neuropeptides.

Gene Full Name: secretogranin III

Sequence Similarities: Contains 2 Ig-like C2-type (immunoglobulin-like) domains.

Gene ID: 29106

UniProt: Q8WXD2