SCLY antibody (C-Term) (Biotin)

Catalog No. ABIN8035439

This Rabbit Polyclonal antibody specifically detects SCLY in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for SCLY antibody (C-Term) (Biotin) (ABIN8035439)

Target: SCLY (Selenocysteine Lyase (SCLY))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCLY antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-SCLY Antibody (Biotin)

Binding Specificity: C-Term

Purpose: Anti-Selenocysteine lyase SCLY Antibody Biotin Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human SCLY.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SCLY

Target: SCLY (Selenocysteine Lyase (SCLY))

Alternative Name: SCLY

Background:

Background: SCLY (Selenocysteine Lyase), is an enzyme that catalyzes the chemical reaction. This enzyme belongs to the family of lyases, specifically the class of carbon-sulfur lyases. The International Radiation Hybrid Mapping Consortium mapped the human SCLY gene to chromosome 2. Mihara et al. (2000) showed that mouse Scly catalyzed the conversion of L-selenocysteine to L-alanine. Scly activity required pyridoxal 5-prime phosphate, was specific to L-selenocysteine, and showed maximum reactivity at pH 9.0.

Gene Full Name: selenocysteine lyase

Sequence Similarities: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

Gene ID: 51540

UniProt: Q96I15

Pathways: Stem Cell Maintenance