SCLY antibody (C-Term)

Catalog No. ABIN8035449

The Rabbit Polyclonal anti-SCLY antibody is suitable to detect SCLY in samples from Human. It has been validated for WB.

Quick Overview for SCLY antibody (C-Term) (ABIN8035449)

Target: SCLY (Selenocysteine Lyase (SCLY))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCLY antibody is un-conjugated

Application: Western Blotting (WB)

Grade: Carrier-free

Product Details anti-SCLY Antibody

Binding Specificity: C-Term

Purpose: Anti-Selenocysteine lyase SCLY Antibody

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-Selenocysteine lyase SCLY Antibody. Tested in WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human SCLY.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Sodium azide, Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for SCLY

Target: SCLY (Selenocysteine Lyase (SCLY))

Alternative Name: SCLY

Background:

Background: SCLY (Selenocysteine Lyase), is an enzyme that catalyzes the chemical reaction. This enzyme belongs to the family of lyases, specifically the class of carbon-sulfur lyases. The International Radiation Hybrid Mapping Consortium mapped the human SCLY gene to chromosome 2. Mihara et al. (2000) showed that mouse Scly catalyzed the conversion of L-selenocysteine to L-alanine. Scly activity required pyridoxal 5-prime phosphate, was specific to L-selenocysteine, and showed maximum reactivity at pH 9.0.

Gene Full Name: selenocysteine lyase

Sequence Similarities: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

Molecular Weight: 85-91 kDa

Gene ID: 51540

UniProt: Q96I15

Pathways: Stem Cell Maintenance