Septin 6 antibody (AA 1-434) (Biotin)

Catalog No. ABIN8035726

The Biotin-conjugated Rabbit Polyclonal anti-Septin 6 antibody (ABIN8035726) specifically detects Septin 6 in WB, IHC and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Septin 6 antibody (AA 1-434) (Biotin) (ABIN8035726)

Target: Septin 6 (SEPT6)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Septin 6 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-Septin 6 Antibody (Biotin)

Binding Specificity: AA 1-434

Purpose: Anti-SEPT6/SEPTIN6 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SEPT6/SEPTIN6 recombinant protein (Position: M1-E434).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Septin 6

Target: Septin 6 (SEPT6)

Alternative Name: SEPTIN6

Background:

Background: Septin-6 is a protein that in humans is encoded by the SEPT6 gene. This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined.

Gene Full Name: septin 6

Gene ID: 23157

UniProt: Q14141