SERAC1 antibody (AA 97-623) (Biotin)

Catalog No. ABIN8035803

The Rabbit Polyclonal anti-SERAC1 antibody is suitable to detect SERAC1 in samples from Human, Mouse and Rat. It has been validated for WB, IHC and ELISA.

Quick Overview for SERAC1 antibody (AA 97-623) (Biotin) (ABIN8035803)

Target: SERAC1 (Serine Active Site Containing 1 (SERAC1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SERAC1 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-SERAC1 Antibody (Biotin)

Binding Specificity: AA 97-623

Purpose: Anti-SERAC1 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SERAC1 recombinant protein (Position: E97-H623).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SERAC1

Target: SERAC1 (Serine Active Site Containing 1 (SERAC1))

Alternative Name: SERAC1

Background:

Background: Serine active site-containing protein 1, or Protein SERAC1 is a protein in humans that is encoded by the SERAC1 gene. The protein encoded by this gene is a phosphatidylglycerol remodeling protein found at the interface of mitochondria and endoplasmic reticula, where it mediates phospholipid exchange. The encoded protein plays a major role in mitochondrial function and intracellular cholesterol trafficking. Defects in this gene are a cause of 3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome (MEGDEL). Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene.

Gene Full Name: serine active site containing 1

Gene ID: 84947

UniProt: Q96JX3

Pathways: Inositol Metabolic Process