STK16 antibody (AA 109-268) (Fluoro594)

Catalog No. ABIN8036053

The Fluoro594-conjugated Rabbit Polyclonal anti-STK16 antibody (ABIN8036053) specifically detects STK16 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for STK16 antibody (AA 109-268) (Fluoro594) (ABIN8036053)

Target: STK16 (serine/threonine Kinase 16 (STK16))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STK16 antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-STK16 Antibody (Fluoro594)

Binding Specificity: AA 109-268

Purpose: Anti-STK16 Antibody Fluoro594 Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human STK16 shares 95.6%,96.9% amino acid (aa) sequence identity with mouse,rat STK16,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human STK16 recombinant protein (Position: E109-L268). Human STK16 shares 95.6% and 96.9% amino acid (aa) sequence identity with mouse and rat STK16, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for STK16

Target: STK16 (serine/threonine Kinase 16 (STK16))

Alternative Name: STK16

Background:

Background: Serine/threonine-protein kinase 16 is an enzyme that in humans is encoded by the STK16 gene. Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.Synonyms: MPSK, MPSK1, Myristoylated and palmitoylated serine/threonine-protein kinase, PKL12, Serine/threonine-protein kinase 16, TGF-beta-stimulated factor 1, TSF-1, TSF1

Gene Full Name: serine/threonine kinase 16

Gene ID: 8576

UniProt: O75716