STK3 antibody (AA 314-456) (PE)

Catalog No. ABIN8036090

This Rabbit Polyclonal antibody specifically detects STK3 in FACS. It exhibits reactivity toward Human and Monkey.

Quick Overview for STK3 antibody (AA 314-456) (PE) (ABIN8036090)

Target: STK3 (serine/threonine Kinase 3 (STK3))

Reactivity: Human, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STK3 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-STK3 Antibody (PE)

Binding Specificity: AA 314-456

Purpose: Anti-STK3/MST-2 Antibody PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human STK3/MST-2 recombinant protein (Position: E314-D456).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for STK3

Target: STK3 (serine/threonine Kinase 3 (STK3))

Alternative Name: STK3

Background:

Background: Serine/threonine-protein kinase 3 is an enzyme that in humans is encoded by the STK3 gene. This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C-terminal portion. The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: serine/threonine kinase 3

Gene ID: 6788

UniProt: Q13188

Pathways: Tube Formation