SERPINA7 antibody (AA 55-389) (Biotin)

Catalog No. ABIN8036248

The Biotin-conjugated Rabbit Polyclonal anti-SERPINA7 antibody (ABIN8036248) specifically detects SERPINA7 in WB, IHC and ELISA. The antibody is reactive with Human samples.

Quick Overview for SERPINA7 antibody (AA 55-389) (Biotin) (ABIN8036248)

Target: SERPINA7 (Serpin Family A Member 7 (SERPINA7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SERPINA7 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-SERPINA7 Antibody (Biotin)

Binding Specificity: AA 55-389

Purpose: Anti-Thyroxine Binding Globulin/SERPINA7 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Thyroxine Binding Globulin/SERPINA7 recombinant protein (Position: R55-R389).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SERPINA7

Target: SERPINA7 (Serpin Family A Member 7 (SERPINA7))

Alternative Name: SERPINA7

Background:

Background: Thyroxine-binding globulin (TBG) is a globulin protein that in humans is encoded by the SERPINA7 gene. There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.

Gene Full Name: serpin family A member 7

Gene ID: 6906

UniProt: P05543

Pathways: Hormone Transport