SARS2 antibody (AA 46-518) (PE)

Catalog No. ABIN8036642

This Rabbit Polyclonal antibody specifically detects SARS2 in FACS. It exhibits reactivity toward Human.

Quick Overview for SARS2 antibody (AA 46-518) (PE) (ABIN8036642)

Target: SARS2 (seryl-tRNA Synthetase 2, Mitochondrial (SARS2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SARS2 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-SARS2 Antibody (PE)

Binding Specificity: AA 46-518

Purpose: Anti-SARS2 Antibody PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SARS2 recombinant protein (Position: E46-S518).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SARS2

Target: SARS2 (seryl-tRNA Synthetase 2, Mitochondrial (SARS2))

Alternative Name: SARS2

Background:

Background: Seryl-tRNA synthetase, mitochondrial is an enzyme that in humans is encoded by the SARS2 gene. This gene encodes the mitochondrial seryl-tRNA synthethase precursor, a member of the class II tRNA synthetase family. The mature enzyme catalyzes the ligation of Serine to tRNA(Ser) and participates in the biosynthesis of selenocysteinyl-tRNA(sec) in mitochondria. The enzyme contains an N-terminal tRNA binding domain and a core catalytic domain. It functions in a homodimeric form, which is stabilized by tRNA binding. This gene is regulated by a biional promoter that also controls the expression of mitochondrial ribosomal protein S12. Both genes are within the critical interval for the autosomal dominant deafness locus DFNA4 and might be linked to this disease. Multiple transcript variants encoding different isoforms have been identified for this gene.

Gene Full Name: seryl-tRNA synthetase 2, mitochondrial

Gene ID: 54938

UniProt: Q9NP81