SARS2 antibody (AA 46-518)

Catalog No. ABIN8036644

The Rabbit Polyclonal anti-SARS2 antibody (ABIN8036644) specifically detects SARS2 in WB, ELISA, IHC, ICC and IF. The antibody is reactive with Human samples.

Quick Overview for SARS2 antibody (AA 46-518) (ABIN8036644)

Target: SARS2 (seryl-tRNA Synthetase 2, Mitochondrial (SARS2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SARS2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Grade: Carrier-free

Product Details anti-SARS2 Antibody

Binding Specificity: AA 46-518

Purpose: Anti-SARS2 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-SARS2 Antibody. Tested in ELISA, IF, IHC, ICC, WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SARS2 recombinant protein (Position: E46-S518).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Immunofluorescence, 5 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SARS2

Target: SARS2 (seryl-tRNA Synthetase 2, Mitochondrial (SARS2))

Alternative Name: SARS2

Background:

Background: Seryl-tRNA synthetase, mitochondrial is an enzyme that in humans is encoded by the SARS2 gene. This gene encodes the mitochondrial seryl-tRNA synthethase precursor, a member of the class II tRNA synthetase family. The mature enzyme catalyzes the ligation of Serine to tRNA(Ser) and participates in the biosynthesis of selenocysteinyl-tRNA(sec) in mitochondria. The enzyme contains an N-terminal tRNA binding domain and a core catalytic domain. It functions in a homodimeric form, which is stabilized by tRNA binding. This gene is regulated by a biional promoter that also controls the expression of mitochondrial ribosomal protein S12. Both genes are within the critical interval for the autosomal dominant deafness locus DFNA4 and might be linked to this disease. Multiple transcript variants encoding different isoforms have been identified for this gene.

Gene Full Name: seryl-tRNA synthetase 2, mitochondrial

Molecular Weight: 53 kDa

Gene ID: 54938

UniProt: Q9NP81