SHARPIN antibody (AA 25-325) (Fluoro550)

Catalog No. ABIN8036980

The Fluoro550-conjugated Rabbit Polyclonal anti-SHARPIN antibody (ABIN8036980) specifically detects SHARPIN in FACS. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for SHARPIN antibody (AA 25-325) (Fluoro550) (ABIN8036980)

Target: SHARPIN (SHANK-Associated RH Domain Interacting Protein (SHARPIN))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHARPIN antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-SHARPIN Antibody (Fluoro550)

Binding Specificity: AA 25-325

Purpose: Anti-SHARPIN Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human SHARPIN shares 72.3%,72.6% amino acid (aa) sequence identity with mouse,rat SHARPIN,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SHARPIN recombinant protein (Position: H25-R325). Human SHARPIN shares 72.3% and 72.6% amino acid (aa) sequence identity with mouse and rat SHARPIN, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SHARPIN

Target: SHARPIN (SHANK-Associated RH Domain Interacting Protein (SHARPIN))

Alternative Name: SHARPIN

Background:

Background: Enables polyubiquitin modification-dependent protein binding activity. Involved in defense response to bacterium, protein linear polyubiquitination, and regulation of signal transduction. Located in cytosol. Part of LUBAC complex.

Gene Full Name: SHANK associated RH domain interactor

Gene ID: 81858

UniProt: Q9H0F6