SHROOM1 antibody (AA 371-807) (PE)

Catalog No. ABIN8037084

The Rabbit Polyclonal anti-SHROOM1 antibody is suitable to detect SHROOM1 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for SHROOM1 antibody (AA 371-807) (PE) (ABIN8037084)

Target: SHROOM1 (Shroom Family Member 1 (SHROOM1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHROOM1 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-SHROOM1 Antibody (PE)

Binding Specificity: AA 371-807

Purpose: Anti-SHROOM1 Antibody PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SHROOM1 recombinant protein (Position: R371-D807).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SHROOM1

Target: SHROOM1 (Shroom Family Member 1 (SHROOM1))

Alternative Name: SHROOM1

Background:

Background: SHROOM family members play diverse roles in the development of the nervous system and other tissues. SHROOM1 is a PDZ domain-containing actin-binding protein that is required for neural tube morphogenesis. It facilitates neurulation by regulating the morphology of neurepithelial cells via the apical positioning of an actomyosin network in the neurepithelium. SHROOM1 is also expressed in pulmonary arterial smooth muscle cells and its expression is significantly decreased in mouse and human models of pulmonary arterial hypertension, suggesting that there may be a link between SHROOM1 expression and pulmonary arterial hypertension.

Gene Full Name: shroom family member 1

Gene ID: 134549

UniProt: Q2M3G4