SHROOM1 antibody (AA 371-807)

Catalog No. ABIN8037086

This Rabbit Polyclonal antibody specifically detects SHROOM1 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for SHROOM1 antibody (AA 371-807) (ABIN8037086)

Target: SHROOM1 (Shroom Family Member 1 (SHROOM1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHROOM1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Carrier-free

Product Details anti-SHROOM1 Antibody

Binding Specificity: AA 371-807

Purpose: Anti-SHROOM1 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-SHROOM1 Antibody. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SHROOM1 recombinant protein (Position: R371-D807).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SHROOM1

Target: SHROOM1 (Shroom Family Member 1 (SHROOM1))

Alternative Name: SHROOM1

Background:

Background: SHROOM family members play diverse roles in the development of the nervous system and other tissues. SHROOM1 is a PDZ domain-containing actin-binding protein that is required for neural tube morphogenesis. It facilitates neurulation by regulating the morphology of neurepithelial cells via the apical positioning of an actomyosin network in the neurepithelium. SHROOM1 is also expressed in pulmonary arterial smooth muscle cells and its expression is significantly decreased in mouse and human models of pulmonary arterial hypertension, suggesting that there may be a link between SHROOM1 expression and pulmonary arterial hypertension.

Gene Full Name: shroom family member 1

Molecular Weight: 91 kDa

Gene ID: 134549

UniProt: Q2M3G4